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Cotton Wool Spots
Cotton wool spots have a myriad of causes. Any process that occludes small retinal arterioles will do this: hypertension, diabetes, HIV, severe anemia or thrombocytopenia, hypercoagulable states, connective tissue disorders, viruses, lues, Behçet's and many others. To review the many other yellow-white things in the retina with which you could confuse cotton wool spots, check out Yellow-White Things in the Retina.
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