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1. History
2. Exam
3. Photos
4. Diagnosis
5. Teaching Points
6. Comments

Case 75 Diagnosis

Acute exudative polymorphous vitelliform maculopathy OU

Differential Diagnosis

• Harada’s disease: similarly presents with prodromal headache and bilateral exudative retinal detachments but typically occurs in pigmented individuals and does not have symmetric subretinal yellow deposits
• Ocular lymphoma: typically presents with larger, more irregular and asymmetric subretinal deposits and is accompanied by vitreous cells
• Best vitelliform dystrophy: fluorescein angiography typically shows blocked fluorescence from vitelliform lesion. There is often a positive family history.
• Acute multifocal placoid pigment epitheliopathy: lesions also at the level of the retinal pigment epithelium, but usually more confluent. May be associated with headache, neck pain.