Research by Disease

Age-related Macular Degeneration

• Genetics of Age-Related Macular Degeneration
  John R. Heckenlively, M.D.
• Pharmacologic and Laser Treatment of Age-related Macular Degeneration
  Mark W. Johnson, M.D., David C. Musch, Ph.D., M.P.H.

Amblyopia

• Bilateral Refractive Amblyopia Treatment Study
  Monte A. Del Monte, M.D.
• Development of Vision in Infants
  Steven M. Archer, M.D., Monte A. Del Monte, M.D.
• Impact of Childhood Strabismus Surgery on Social and Emotional Aspects of Quality of Life
  Steven M. Archer, M.D., David C. Musch, Ph.D., M.P.H.

Cornea Disease

• Laser Treatments for Ocular Defects
  Alan Sugar, M.D., H. Kaz Soong, M.D.
• Epidemiological Studies in Ophthalmology, Corneal Transplantation
  David C. Musch, Ph.D., M.P.H

Diabetes and Diabetic Retinopathy

• Pathology of diabetic retinopathy, with the goal of understanding the transformation of the innate immune cells, microglia, within the diabetic retina and the contribution of these cells to neurodegeneration and vascular dysfunction that can lead to vision loss in patients with diabetes.
  Steven F. Abcouwer, Ph.D.
• Investigations into the formation and loss of the blood-brain and blood-retinal barrier in normal vascular biology and diabetes
  David A. Antonetti, Ph.D.
• Growth Factors and Abnormal Retinal Cell Proliferation in Diabetes
  Monte A. Del Monte, M.D.
• Identifying and understanding mechanisms of retinal cell death that occur in neurodegenerative disorders such as diabetes.
  Patrice E. Fort, Ph.D., M.S.
• Pathogenesis and treatment of diabetic retinopathy and alterations in growth factor signaling
  Thomas W. Gardner, M.D., M.S.
• Mechanisms of ocular inflammation and angiogenesis in neurodegeneration and vascular pathophysiology of retina during diabetes
  Cheng-mao Lin, Ph.D.
• Blood retinal barrier breakdown and vascular permeability in diabetic retinopathy
  Arivalagan Muthusamy, Ph.D.
• The Role of Metabolism and Oxidant Damage in Diabetes
  Howard R. Petty, Ph.D.
• Pathophysiology of Diabetic Retinopathy
  Donald G. Puro, M.D., Ph.D.
• Metabolic Imaging for Diabetic Retinopathy
  Victor M. Elner, M.D., Howard R. Petty, Ph.D.
• Pharmacological Treatment of Diabetic Retinopathy and Macular Edema
  Mark W. Johnson, M.D.

Glaucoma

• Glaucoma Treatment Studies
  Paul R. Lichter, M.D., Sayoko E. Moroi, M.D., Ph.D., David C. Musch, Ph.D., M.P.H.
• Genetics of Glaucoma and Other Hereditary Ophthalmic Diseases
  Philip J. Gage, Ph.D., Paul R. Lichter, M.D., Hemant S. Pawar, Ph.D., Julia E. Richards, Ph.D.
• Implications for Glaucoma in Cellular and Molecular Regulation of Aqueous Humor Dynamics
  Sayoko E. Moroi, M.D., Ph.D.
• Clinical Treatment Studies of Ocular Hypertension
  Terry J. Bergstrom, M.D., Sayoko E. Moroi, M.D., Ph.D
• Collaborative Initial Glaucoma Treatment Study
  Paul R. Lichter, M.D., David C. Musch, Ph.D., M.P.H., Julia E. Richards, Ph.D.
• Health services research, patterns of eye care in the United States, outcomes of glaucoma surgery, quality of life of patients with ocular disorders
  Joshua D. Stein, M.D., M.S.
  

Macular Edema

• Pharmacological Treatment of Diabetic Retinopathy and Macular Edema
  Mark W. Johnson, M.D.

Ocular Hypertension

• Clinical Treatment Studies of Ocular Hypertension
  Terry J. Bergstrom, M.D., Monte A. Del Monte, M.D., Sayoko E. Moroi, M.D., Ph.D.

Ocular Oncology

• Investigations into the formation and loss of the blood-brain and blood-retinal barrier in normal vascular biology and cancer
  David A. Antonetti, Ph.D.
• The biology and developmental genetics of extraocular muscles and neural crest-derived stem cells in the orbit and their importance in orbital cancer
  Alon Kahana, M.D., Ph.D.
• Ocular Oncology and Retinal Vascular Diseases
  Donald G. Puro, M.D., Ph.D.

Optic Neuritis and Optic Neuropathy

• Clinical Studies of Optic Neuritis and Optic Neuropathy
  Wayne T. Cornblath, M.D., Jonathan D. Trobe, M.D.

Ptosis and Browtosis

• Surgical Correction of Ptosis
  David C. Musch, Ph.D., M.P.H.
• Mid-Facial Surgery: Outcomes and Quality of Life
  Christine C. Nelson, M.D., David C. Musch, Ph.D., M.P.H.

Retina Detachments and Inherited Degenerations

• Mouse Models of Retinal Degeneration
  John R. Heckenlively, M.D
• Molecular Genetics of Retinal Dystrophies
  John R. Heckenlively, M.D., Debra A. Thompson, Ph.D.
• Determining phenotype-genotype correlations and predictive value of metabolic and functional testing in Stargardt disease
  K. Thiran Jayasundera, M.D.
  
• Function and Regulation of RPE-Specific Proteins
  Debra A. Thompson, Ph.D.
• Retinal Cell Death: Basic Mechanisms and Neuroprotective Strategies
  David N. Zacks, M.D., Ph.D.

Retinitis Pigmentosa

• Human Inherited Retinal Diseases: Causes and Treatments
  John R. Heckenlively, M.D., Debra A. Thompson, Ph.D.

Strabismus

• Development of Vision in Infants
  Steven M. Archer, M.D., Monte A. Del Monte, M.D.
• Esotropia Treatment Study
  Monte A. Del Monte, M.D.
• Impact of Childhood Strabismus Surgery on Social and Emotional Aspects of Quality of Life
  Steven M. Archer, M.D., David C. Musch, Ph.D., M.P.H.
• Development and regeneration of extraocular muscles.
  Alon Kahana, M.D., Ph.D.
  

Telangiectasia

• Mouse Models and Genetic Studies of Telangiectasia
  John R. Heckenlively, M.D.

Thyroid Eye Disease

• Graves' eye disease, autoimmune diseases of the orbit, minimally invasive approaches to the orbit
  Raymond S. Douglas, M.D., Ph.D.
• The biology and developmental genetics of extraocular muscles and neural crest-derived stem cells in the orbit and their importance in thyroid-related eye disease
  Alon Kahana, M.D., Ph.D.
• Autoimmune thyroid disease, extracellular matrix, cell signaling, gene expression, ecosanoids, inflammation and cytokine action
  Terry J. Smith, M.D.

Uveitis and Other Immune Eye Diseases

• Immune mechanisms responsible for disease remission (uveitis) during pregnancy
  Howard R. Petty, Ph.D.
• Autoimmune Retinopathy
  Victor M. Elner, M.D., John R. Heckenlively, M.D., Howard R. Petty, Ph.D.
• Pathogenesis and Inflammation of the Outer Retina
  Susan G. Elner, M.D., Victor M. Elner, M.D., Ph.D., Howard R. Petty, Ph.D. 
• Graves' eye disease, autoimmune diseases of the orbit, minimally invasive approaches to the orbit
  Raymond S. Douglas, M.D., Ph.D.

Vitreoretinal Surgery

• Pharmacologic Adjuncts to Vitreoretinal Surgery
  Mark W. Johnson, M.D.