David N. Zacks, M.D., Ph.D.
Publications

• Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Corton M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A. Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci USA 2010;107:7401-7406.
• Zacks DN. Gene transcription profile of the detached retina (An AOS Thesis). Trans Am Ophthalmol Soc 2009;107:343-382.
• Stein JD, Zacks DN, Grossman D, Grabe H, Johnson MW, Sloan FA. Adverse events after pars plana vitrectomy among medicare beneficiaries. Arch Ophthalmol 2009;127:1656–1663.
• Besirli CG, Chinskey ND, Zheng QD, Zacks DN. Inhibition of retinal detachment-induced apoptosis in photoreceptors by a small peptide inhibitor of the fas receptor. Invest Ophthalmol Vis Sci 2010;51:2177-2184. Epub 2009 Oct 22.
• Zadro-Lamoureux LA, Zacks DN, Baker AN, Zheng QD, Hauswirth WW, Tsilfidis C. XIAP protects photoreceptors from retinal detachment-induced apoptosis. Invest Ophthalmol Vis Sci. 2009;50:1448-1453. Epub 2008 Dec 5.
• Chong D, Boehlke CS, Zheng QD, Zhang L, Han Y, Zacks DN. Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci 2008;49:3193-3200. Epub 2008 Mar 31.
• Zacks DN, Boehlke C, Richards AL, Zheng QD. Role of the fas-signaling pathway in photoreceptor neuroprotection. Arch Ophthalmol 2007;125:1389-1395.
• Ronan SM, Yoganathan P, Chien FY, Corcostegui IA, Blumenkranz MS, Deramo VA, Elner SG, Fastenberg DA, Johnson MW, Lopez M, Mateo C, Moshfeghi DM, Navarro R, Rosenblatt BJ, Sanislo SR, Saxe SJ, Zacks DN. Retinal pigment epithelium years after intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration. Retina 2007;27:535-540.
• Leveque TK, Yu L, Musch DC, Chervin RD, Zacks DN. Central serous chorioretinopathy and risk for obstructive sleep apnea. Sleep Breath 2007;11:253-257.
• Downs K, Zacks DN, Caruso R, Karoukis AJ, Branham K, Yashar BM, Haimann MH, Trzupek K, Meltzer M, Blain D, Richards JE, Weleber RG, Heckenlively JR, Sieving PA, Ayyagari R. Molecular testing for hereditary retinal disease as part of clinical care. Arch Ophthalmol 2007;125:252-258.
• Ament CS, Zacks DN, Lane AM, et al.Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture. Arch Ophthalmol 2006;124:957-966.
• Atmaca-Sonmez P, Johnson MW, Zacks DN. Persistent detachment of the fovea after non-buckling repair of rhegmatogenous retinal detachment. Br J Ophthalmol 2006;90:920-921.
• Zacks DN, Han Y, Zeng Y, Swaroop A.Activation of signaling pathways and stress-response genes in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci 2006;47:1691-1695.
• Reck SD, Zacks DN, Eibschitz-Tsimhoni M.Retinal and intracranial arteriovenous malformations: Wyburn-Mason syndrome. J Neuroophthalmol 2005;25:205-208.
• Bucher RS, Hall E, Reed DM, et al. Effect of intravitreal triamcinolone acetonide on susceptibility to experimental bacterial endophthalmitis and subsequent response to treatment. Arch Ophthalmol 2005;123:649-653.
• Tsina EK, Lane AM, Zacks DN, et al. Treatment of metastatic tumors of the choroid with proton beam irradiation. Ophthalmology 2005 ;112:337-343.
• Zink JM, Singh-Parikshak R, Johnson CS, Zacks DN. Hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome. Graefe's Arch Clin Exp Ophthalmol 2005;243:386-388.
• Zacks DN, Johnson MW. Combined intravitreal injection of triamcinolone acetonide and panretinal photocoagulation for concomitant diabetic macular edema and proliferative diabetic retinopathy. Retina 2005;25:135-140.
• Zacks DN, Zheng QD, Han Y, Bakhru R, Miller JW. FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment. IOVS 2004;45(12):4563-4569.
• Zacks DN. Neisseria meningitidis endophthalmitis. Ophthalmology 2004;111:1432-1433.
• Zacks DN, Johnson MW. Trans-retinal pigment migration: An OCT study. Arch Ophthalmol 2004;122:406-408.
• Zacks DN, Johnson MW. Retinal angiomatous proliferation: OCT confirmation of an intraretinal lesion. Arch Ophthalmol 2004;122:932-933.
• Zhao JC, Zacks DN, Gragoudas ES, Pasquale LR. Pupil-sparing excision of an atypical iris melanocytoma induces remission of secondary glaucoma. BJ Ophthalmol 2004;88:842-843.
• Zacks DN, Hänninen V, Pantcheva M, Ezra E, Grosskreutz C, Miller JW. Caspase activation in an experimental model of retinal detachment. IOVS 2003;44(3):1262-1267.
• Zacks DN, Samson CM, Loewenstein J, Foster CS. Electroretinograms as an indicator of disease activity in birdshot retinochoroidopathy. Graefe's Arch Clin Exp Ophthalmol 2002;240(8):601-607.
• Zacks DN, Ezra E, Terada Y, Michaud N, Connolly E, Gragoudas ES, Miller JW. Verteporfin photodynamic therapy in the rat model of choroidal neovascularization: angiographic and histologic characterization. IOVS 2002;43:2384-2391.
• Zacks DN, Hart LJ, Young LHY. Ultrasound in the traumatized eye: intraocular foreign body versus artifact. Int Ophthalmol Clin 2002;42(3):121-128.
• Zacks DN, Pinnolis MK, Berson EL, Gragoudas ES. Melanoma-associated retinopathy and recurrent exudative detachments in a patient with choroidal melanoma. Am J Ophthalmol 2001;132(4):578-581.
• Zacks DN, D'Amico DJ. Maculopathies that resemble optic neuropathies. Int Ophthalmol Clin 2001;41(1):61-71.
• Nguyen QD, Uy HS, Akpek EK, Zacks DN, Foster CS. Choroidopathy of systemic lupus erythematosus. Lupus 2000;9(4):288-298.
• Zacks DN, Rizzo JF. The diagnostic challenge of occult large vessel ischemia of the retina and choroid. Curr Opinion Ophthalmol 1999;10(6):371-375.
• Zacks DN, Foster BS, D'Amico DJ. A retained intraocular needle 2 years after cataract extraction. Arch Ophthalmol 1999;117:691.
• Spudich JL, Zacks DN. Microbial sensory rhodopsins. Biomembranes 1996;2(A):199-226.
• Spudich JL, Zacks DN, Bogomolni RA. Microbial sensory rhodopsins: photochemistry and function. Isr J Chem 1995;35:495-513.
• Zacks DN, Spudich JL. Gain setting in Chlamydomonas reinhardtii:Mechanism of phototaxis and the role of the photophobic response. Cell Motil Cytoskel 1994;9(3):225-230.
• Zacks DN, Derguini F, Nakanishi K, Spudich JL. Comparative study of phototactic and photophobic receptor chromophore properties in Chlamydomonas reinhardtii. Biophys J 1993;65:508-518.
• Lawson M, Zacks DN, Derguini F, Nakanishi K, Spudich JL. Retinal analog restoration of photophobic responses in a blind Chlamydomonas reinhardtii mutant: Evidence for an archaebacterial-like chromophore in a eukaryotic rhodopsin. Biophys J 1991;60:1490-1498.